Health & Fitness

Lifesaving application - Safe dosage of particular medicine

Lifesaving application - Safe dosage of particular medicine

Postby briangilbert » Thu May 21, 2009 7:30 am
Many patients are killed by miscalculation of medicine dosage. Is it possible to ask W|A whether a particular dosage for a particular category of patient (Adult/Child/weight...) is within the safe limits.
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Re: Lifesaving application - Safe dosage of particular medicine

Postby jacobr » Thu May 21, 2009 12:11 pm
Sources: epocrates (proprietary), Wolters-Kluwer or FirstDatabank (Proprietary) .. unfortunately - the "safe dose" isn't available in RxNorm (public domain)
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Re: Lifesaving application - Safe dosage of particular medicine

Postby PEHowland » Thu May 21, 2009 5:02 pm
I suspect this would leave Wolfram open to legal claims whenever someone got it wrong. Will probably never happen.
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Re: Lifesaving application - Safe dosage of particular medicine

Postby jehh87 » Tue May 26, 2009 4:43 pm
In the UK we use BNF.org which although not being GNU it is free to register.

Drug dose calculations would be a really good thing to add though. E.g. A patient requires 125mg of a drug three times a day, vial contains 500mg per ml. How much is given over a 24 hour period?

I would know where to start to input that into w¦a without doing most of the math myself!
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Re: Lifesaving application - Safe dosage of particular medicine

Postby sdecherney » Fri Sep 04, 2009 1:12 am
There are limits for the safety of drugs and these are approved by the FDA, published by the pharmaceutical firm as dosage forms on the package insert. W/A could publish dosage amounts, but these are not really clear as individuals may have different tolerances, depending on clinical condition. For example, patients with compromised kidney or liver function usually have a lower limit of safety than normals.

There are a number of places on the internet with useful information such as drug-drug interactions. iGuard, which is free, is a personalized source. You sign up, enter your meds and iGuard returns potential problems or gives you an all clear message [disclaimer: I used to manage iGuard, but have no current financial interest in it.] WebMd/MedScape also has a boat load of useful informaton for consumers.

All of that noted, there are formulae for calculating dosages given body weight, age, gender, etc that could be posted on W/A. They are published and would not likely cause liability.
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Re: Lifesaving application - Safe dosage of particular medicine

Postby belajhon » Wed Oct 06, 2010 5:06 am
Yes i agree... Many of the people died just because of the over dosage. People should have patience and take medicine as according to the doctor advice.
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Re: Lifesaving application - Safe dosage of particular medicine

Postby briangilbert » Wed Oct 06, 2010 5:36 pm
Thanks for all the comments. I agree that the application would be for the use of trained staff. They could key in a complete list of prescriptions planned for the patient and W|A would assess it against all its info. It would then output any clashes cpmplete with sources for further consideration.

W|A could also do drug unit conversions with warnings if the result clashed with any data it had on maximum and minimum dosage.In the early days of metrication many staff doing conversions got the decimal point in the wrong place.
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Re: Lifesaving application - Safe dosage of particular medicine

Postby tryggvirafn » Tue Dec 20, 2011 5:37 pm
I think it is a good idea but not so easy to implement in practice due to various reasons, legal and otherwise, but something that might save lives if done correctly.
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Re: Lifesaving application - Safe dosage of particular medicine

Postby briangilbert » Tue Dec 20, 2011 6:00 pm
tryggvirafn wrote:I think it is a good idea but not so easy to implement in practice due to various reasons, legal and otherwise, but something that might save lives if done correctly.


The thing about WA is that it is intended to quote sources for both the source data and it's algorithms. So any challenge could be referred to the sources. Decisions as to the use of WA would be subject to confirmation by a medically qualified person as is expected where prescriptions are concerned.
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Re: Lifesaving application - Safe dosage of particular medicine

Postby nortski » Tue Jan 10, 2012 2:30 pm
Also; the person giving the dose has to be competent at doing this.
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Re: Lifesaving application - Safe dosage of particular medicine

Postby Nuclearman » Tue Jan 10, 2012 5:48 pm
You guys really should read the terms of use every now and then... W|A already has such a disclaimer, so there really isn't much preventing it, other than getting the data curated. Also it wouldn't be too difficult to list several different "safe dose" values. Though perhaps "common dose" values would be more useful (safe seeming to be on the high side of the common dose values).

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